Ask yourself what you are trying to do. If you want a hot rod, or a race car then go with the v-8. If you want a charming old pickup that can shoulder any load and get the job done then stay with the six. Right now I am keeping my 235 because it runs well and doesn't need a lot of work. I have no delusions of pulling HP out of it though. It will chug down the highway at 55-60 and get around town. I think that some power adders are a good idea, but don't expect v-8 horsepower gains in a inline motor.
That being said....do what the hell you want. That is the best part of customizing. Does it matter what we all think? NO!!! This is a truck for you and you alone. Do what you want and let us know how it turns out.
Kyle