292 with a 200-r4 trans. Torquey motor, and with the right head mods makes good higher rpm power. dual carbs for looks and performance (4 bbl if you don't want the cool factor)

200 trans is plenty strong, lighter than the other ODs that will bolt to the standard chevy pattern, better gear ratios for your use and overall size is smaller/lighter.

You should wind up lighter overall than stock and with plenty of power, and if dressed right the six looks great.