I have a 3/4 ton full-floater Dana 60 from a GMC pickup under my 59 Burb, and the tires are a VERY close fit inside the fenders, enough that I had to do a little hammer work to keep them from rubbing. It's been parked for several years, and when I get around to putting it back on the road, I'm going to build up some custom-offset wheels so I can do a proper restoration on the wheel openings. I used a set of Ford 3.73 gears, and a Dodge pinion flange when I set it up, since the rear end was given to me with a broken pinion gear, and no input flange. All Dana 60's have interchangeable parts, regardless of what vehicle they were in originally. Even some International trucks ran Dana rear ends.
Jerry