There's a whole page on this in the tech tips section:
http://50chevy.freeservers.com/Suspension_Widths.html#SuspensionIf your S-10 has 2" wide brakes, this puts the wheel flanges at about 57", which is going to be too narrow.
I have a '66 Chevy pickup axle that has 58" between drums, 62" between flanges. It has a 3.07 gear ratio and six lug bolt pattern. That is my #1 suggestion for interchangability. Its slightly wide but not noticable, about 1/2" per side according to my measurements on my Chevy. The spring perches have to be changed, though, the 66 is out of a coil spring truck.
