If you want leaf springs in the rear and IFS in the front I think the S-10 is a good option. But if you are happy with rear leaf you have to ask why not use the orginal frame.
There are lots of reasons not to do a clip, and doing a search here will probably find you a few hundred of them so I won't try to repeat them.
My responses sound like I'm against making the change. I'm not, but I think its very important to know why you are making such a significant change before tackling the project.
I always want someone to tell me what they think 'best' means before trying to tell them what is best for them.
I'm working on five different truck projects and on two of them I'm planning to use the orignal frames. I think I have the best plan for each and that gives me a different answer on each project.
You really want to think through how you want to use the truck and how you want it to perform before making this kind of decision. If you want an S-10 that looks like an AD truck the S-10 swap might very well be your best approach.
