I did some experimenting with speakers in my truck and discovered that any more than 2 speakers (not counting sub-woofs) just added confusion to the sound. A truck cab is too small for more than two speakers ... the sound bounces around too much and clarity is lost.
I put a simple stereo radio/cassette player in my truck and a pair of Sony Xplod speakers -- in the floor kickpanels (way better than in the doors) and it turned out great!
Check out my radio install
Here Check out my speaker install
Here