The 250 block has a weak head bolt at the right front corner. The water pump opening crowds the head bolt. If you torque the head down with the same torque on all the bolts, you cn easily break the block. That one bolt gets less torque. I broke the first one I built, it seeped coolant for a couple years till I changed it out. The 292 doesn't have that issue. Camshafts are also different. I would bet the rest of the block is very similar.
Thanks I'll pass that on. I think he's more concerned about the bottom end but I'll leave that to the experts. That is not me.
Perhaps this was already asked:
Does the V12 engine have the same 4.40" bore pitch as the 250/292 L6?
Yes it does. The valve order is different. The V-12 head alternates instead of being grouped to avoid hot spots. The push rod angle is off but I think manageable. If I remember with my crude measuring method the worst on was 4 degrees offset. Most were under 1.5 degrees. Some of the big block heads has crazy push rod angles.
