I agree with Jason. The spec for my F250 7.3L is 50 mA or less when everything is asleep.
When you say new regulator/generator, if it's actually an alternator, it's very likely that a diode has shorted and the battery is trying to power the alternator as a motor. That'll drain the battery in short order. It may still charge the battery normally.
Easy to check. Pull the power wire off the generator and see if the draw goes away.