Thank you for all the additional input.
While I am not in a "drive it while work on the body" situation per say, and I have been priming (using various epoxy primers) as I work on various panels and they have been exposed to the air and related humidity in my garage. For some parts it could be months. I am hoping that the epoxy primer will be viable such that I do not need to remove all of it to reprime prior to painting.
MNSmith, I agree and that is why I do not plan to paint in the heated portion of my garage resultig in the potential temperature delima as fall is upon us.