Not likely- - - -either one can probably handle 80 over, but 60 is more likely to be longer lasting and have less of a possible problem with overheating. A 60 over 216 with a 235 crankshaft results in 235 cubic inches in a 216-appearing block. The lightweight aluminum pistons will really wake up an engine that once had cast iron ones! Quicker acceleration, and higher RPM. I'm also working on a radically modified 216 with a stroker crankshaft that will have 258 cubic inches, H-beam connecting rods, roller valve lifters and stud-mounted roller rocker arms.
Jerry