I my case I have a SBC 383 with an NV3500 5 speed (rather than your 4 speed) but I needed to drop the center section of the cross member to clear the transmission. The only way to really tell with your combination is to try it. Much easier with the cab removed but even with the cab in place you can determine if the engine-transmission combination will clear the cross member byt trying to get the engine into location.

1949/50 3600 Project
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