I have run 216s, 235s, and 261s.

Each "step up" resulted (as expected) in a noticeable difference in power.

Another "swap" that results in a noticeable different in gas mileage and "smoother" running is to install the 3.55 rear-end conversion gear-set (R&P Ring&Pinion set sold my MotherTrucker). Buy and use an installation-parts kit that is available from a few old-chevy-parts vendors.