Given your tires are 26 in tall with your set up 50 mph you'll be turning 2,500 rpm , just coming on its power band , 3000 rpm will give you roughly 65 mph
which will make the 6 cyl music a little louder , but shouldn't bother the motor if its in fair shape .
Sounds to me that you might over gear your truck to the point that you'll loose performance.
What's the over drive ratio on your Tremec

John


good planning is no substitute for dumb luck