"Something like a Chevy S 10" is going to have a 5 lug wheel bolt pattern (unless it's from a 4x4) and require an open driveline which means a different transmission. There should be a lot of the closed drive line rear ends available from guys that made conversions.
Fred


1956 3100 Pickup/Red/350/3sp OD/PS/Disc Brakes
1957 Bel Air Sport Coupe/Red/355/TH350/PS/Disc Brakes
2017 Silverado LT Single Cab SB/Black/5.3/6 Speed Trans
1947 Willys CJ2A w/F-Head engine