David, nothing on these old girls was designed for todays highway speeds, handling would be my biggest fear. Even with new brakes, tires, engine, aux. trans I don't think you will be happy with the unit for 2500(5000) mile trips. I would look for a modern straight truck the same approximate dimensions and swap the '53 cab/front end over to it. My 57 with 7.2 rear axle tops out at 45 mph against the governor, Chevrolet says 4000 RPM was the intended speed.
