As far as plumbing/smog removal, it depends on the year of the motor. Nice to know what vehicle it came from also.
As far as physical fit of motor and what headers fit. You need to mock up the motor install, and see where the problems are in your particular case. You need to mock it up for all kinds of reasons, not just exhaust. So that is the next step. You are going to install it anyway, so take off front clip and begin.
There is a LT-1 (LT dash 1) 1970-1972.....no smog. Then LT1 in 1991 and up...........smog
By mocking the motor into place you will be able to ask specific questions and some of your questions will be answered by observation. The available space for headers will be identified. Your question about what you will encounter is hard to answer. I assume it means issues regarding overall install of motor. If someone has put the same generation LT1 in the same basic truck, they will respond I guess.
"Without any research at this time" I would recommend searching SBC into an AD on here. Been done many times. The plumbing is a separate issue.
