A tall enough ceiling and regular panel type garage door that rises all the way up before turning flat on the ceiling may not take up any more or less space than a roll up door. You can also get marginally insulated panel type doors, not sure about insulated roll up doors.
Bigger is generally better except for initial cost and ongoing expenses like heat and or AC. So "Bigger" might not be the best answer if you carefully consider your needs and desires. A garage just the right size with efficient layout and storage ideas might be better than a jumble of junk in a very large garage.
Not yet mentioned is storage space and use of pallet racks. I have a tall garage and pallet racks on the back wall make great storage even for heavy stuff like engines and transmissions. Having a forklift to make good use of pallet racks is either yet another expense, a luxury, or necessity depending on your situation.
I'm considering rearranging things in my shop to use more pallet racks along one of the long walls keeping workbench space open under them instead of or in addition to racks on the back wall.
If you're planning on a lift that may or may not help with use of the floor space. I can fit (store) 3 or 4 trucks two wide by two deep in my long skinny garage now but probably only 2 end to end (with 3rd on lift) if/when I install a lift.
