Dan,
I have done this on two sets of original 1954 6.50 x 16 OEM 1/2 ton Chevrolet rims/wheels.
Cooper and Goodyear - LT 215/85R16 Radial - black-walled
Cooper set, with radial inner tubes (and and valve-stem protectors) is it at least 12 years old (at least 10K miles).
Goodyear set, which did not need inner-tubes, is only 5-6 years old (but, no driving on them yet).
Both are garaged vehicles.
I have to "play" with the psi to achieve the best balance between easy "tracking"/steering and no "wandering".
Due to the relatively narrow wheels, they do not look like low-profile radials, and they help cruising MPG because they are 31.5" rolling diameter.
I have no regrets, and no concerns, regarding using truck radial tires (with or without tubes). They are much better than any bias ply tires I have used.
