Be sure you're turning them the right direction- - - -the studs on the driver's side of a left hand drive vehicle have left hand threads. Of course, it you've gotten the outer wheels off already, you have probably discovered that. Budd-style wheels are usually installed with a 1" square drive impact wrench that's capable of over 1,000 ft/lbs. of torque, so you'll need a LONG lever if you're trying to remove them by hand! I use a 4 foot long piece of water pipe as a cheater bar.
Sometimes the really tight ones need some attention from an acetyline torch and penetrating oil before they break loose.
Jerry