I use my 46 2-ton weekly for my business. Mostly stock except for the disc brakes I made for the front. I still have the splash lubricated rods.
I have had a LOT of weight on the back and it still did great. It's not fast. I can run 55 without too much trouble. I have seen my GPS speedometer at 63, but that wasn't comfortable. 55 wasn't too bad, but wouldn't want to hold it there for hours...
A little maintenance every now and then on the brakes and you should be good. Shifting can take a little bit to learn, but once you do the non synchromesh isn't bad. Can easily add an electric wiper motor. I even have a large heater in the cab that keeps it nice and toasty for the winter.
If it's an art deco truck you want, don't let the mechanicals turn you away. I love driving my truck all year round. Unless it's pouring down rain!