I don't, never have, and have no regrets about not doing so.
I do try to buy ethanol free gas wherever possible. One reason is the trouble it can cause with rubber parts and the water it can bring into the system. Another is the fuel economy, it takes more ethanol than 100% gas to go the same mile, which means your uneducated carburetor needs to give the engine more fuel or it will run a little lean on ethanol blended fuel.

•1951 GMC 250 in the Project Journals
•1948 Chevrolet 6400 - Detroit Diesel 4-53T - Roadranger 10 speed overdrive - 4 wheel disc brakes
•1952 Chevrolet 3800 pickup
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"First, get a clear notion of what you desire to accomplish, and then in all probability you will succeed in doing it..." -Henry Maudslay-