Good to see another Buick conversion!
I have a half ton panel with a built 455 Buick in it, but it's two wheel drive.

Here's a tip:
To mount the Buick in the frame, I found that a TransDapt tubular engine conversion mount for a Ford 460 has just about the correct engine mount centerline dimensions for stock Buick motor mounts.

All I had to do was shave some material off the mounting boss on the TransDapt unit to allow the Buick engine side mount to drop over it. Eight large bolts
are used to attach the TransDapt to the inside of the frame rails. This , inherently,
creates an additional crossmember for strength. Whether you box or not, this is an easier way to mount that big Buick than spending a lot of time fabricating. The engine sits nice and low in the chassis and I was able to use the stock exhaust manifolds. Plus, you can tuck it up nice and close to the firewall.

Also, on this conversion I used an oil filter re-location kit, so I would not have to notch the front frame crossmember to clear the Buick housing. In my case I mounted the oil filter right on the passenger side inner fender. Hope this is helpful.
mike