I think doing a chassis swap on anything would require some sort of suspension rebuilding, let alone a 60 year old truck front end.
S10's weren't really known for having trouble free front ends either. Weak ball joints and idler arm.
I had 180,000 miles on my Trailblazer before I needed any suspension work. I replaced the outer tie-rods, the strut arm bushings are worn, but I'll fix that another day.